<i>CYP2C19</i> Phenotype, P2Y <sub>12</sub> Inhibitor Selection, and Clinical Outcomes in Patients on Maintenance Clopidogrel Therapy

Patients on maintenance clopidogrel at the time of percutaneous coronary intervention represent a higher-risk patient population than patients who are naïve to P2Y<sub>12</sub> inhibitors and genotype-guided P2Y<sub>12</sub> inhibitor selection at the time of percutaneous coronary intervention may not provide clinical benefit.

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Publication Details

Journal
Journal of the American Heart Association
Published
2025-07-04
DOI
https://doi.org/10.1161/jaha.125.041634
Citations
1
Primary Topic
Antiplatelet Therapy and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
1.39
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article

CYP2C19 Phenotype, P2Y 12 Inhibitor Selection, and Clinical Outcomes in Patients on Maintenance Clopidogrel Therapy

Luis Ortega‐Paz, William Yang, Francesco Franchi, Marshall Winget et al.
1 citations
Journal of the American Heart Association
Antiplatelet Therapy and Cardiovascular Diseases
1.39
article

CYP2C19 Phenotype, P2Y 12 Inhibitor Selection, and Clinical Outcomes in Patients on Maintenance Clopidogrel Therapy

Luis Ortega‐Paz, William Yang, Francesco Franchi, Marshall Winget, Dominick J. Angiolillo, Anh B. Nguyen, Julio D. Duarte, Ellen C. Keeley, Sanjay Venkatesh, J. Rossi, Larisa H. Cavallari, Cameron D. Thomas, Craig R. Lee, Natasha Kulick, George A. Stouffer, Amber L. Beitelshees, Rajiv Patel
article en
1 citations

Abstract

Patients on maintenance clopidogrel at the time of percutaneous coronary intervention represent a higher-risk patient population than patients who are naïve to P2Y<sub>12</sub> inhibitors and genotype-guided P2Y<sub>12</sub> inhibitor selection at the time of percutaneous coronary intervention may not provide clinical benefit.

Journal of the American Heart AssociationVol. 14(14)
University of North Carolina at Chapel Hill (US), University of Maryland, Baltimore (US), University of Florida (US)
Good health and well-being
Openalex Percentile: Top 17%
Antiplatelet Therapy and Cardiovascular Diseases
1.39
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<i>CYP2C19</i> Phenotype, P2Y <sub>12</sub> Inhibitor Selection, and Clinical Outcomes in Patients on Maintenance Clopidogrel Therapy — Luis Ortega‐Paz, William Yang, et al. · Journal of the American Heart Association (2025) | TGRS Research Map | TGRS