Association Between Mineralocorticoid Receptor Antagonist Use With Worsening Renal Function and Prognosis in Patients With Acute Heart Failure
Initiating an MRA during AHF hospitalization was associated with better postdischarge outcomes in HFrEF, irrespective of creatinine elevation, whereas no such consistent association was observed in HFmr/pEF.
Authors
- Yudai Fujimoto (ORCID: https://orcid.org/0009-0004-8286-3228)
- Eiichi Akiyama (ORCID: https://orcid.org/0000-0001-7333-1909)
- Keisuke Kida (ORCID: https://orcid.org/0000-0002-3464-6016)
- Maki Nogi
- Mitsunobu Kitamura (ORCID: https://orcid.org/0000-0002-7573-7176)
- Yuya Matsue (ORCID: https://orcid.org/0000-0003-2456-8525)
- Shogo Oishi
- Shun Kohsaka (ORCID: https://orcid.org/0000-0003-3779-2972)
- Yasuki Nakada (ORCID: https://orcid.org/0000-0003-0510-6923)
- Takashi Kohno (ORCID: https://orcid.org/0000-0003-2604-1284)
- Yoshihiko Saito (ORCID: https://orcid.org/0000-0001-5574-3571)
- Masayoshi Yamamoto (ORCID: https://orcid.org/0000-0002-1447-9126)
- Tomoya Ueda (ORCID: https://orcid.org/0000-0002-0656-3336)
- Takahiro Okumura (ORCID: https://orcid.org/0000-0001-5076-2052)
- Yuji Nagatomo (ORCID: https://orcid.org/0000-0002-3430-4614)
- Kazutaka Nogi (ORCID: https://orcid.org/0000-0003-0516-8753)
- Tsutomu Yoshikawa (ORCID: https://orcid.org/0000-0002-1619-268X)
- Rika Kawakami (ORCID: https://orcid.org/0000-0002-2904-4993)
- Satomi Ishihara (ORCID: https://orcid.org/0000-0002-2816-4926)
- Takeshi Kitai (ORCID: https://orcid.org/0000-0003-2416-5865)
- Satoshi Suzuki (ORCID: https://orcid.org/0000-0002-3548-1604)
- Yasuyuki Shiraishi (ORCID: https://orcid.org/0000-0001-8788-1186)
Institutions
- Fukushima Medical University (JP)
- National Archives and Records Administration (US)
- University of Tsukuba (JP)
- St. Marianna University School of Medicine (JP)
- Kyorin University (JP)
- Keio University (JP)
- Yokohama City University Medical Center (JP)
- Juntendo University (JP)
- National Cerebral and Cardiovascular Center (JP)
- Nara City Hospital (JP)
- Nara Medical University Hospital (JP)
- Saiseikai Suita Hospital (JP)
- Himeji Medical Center (JP)
- Sakakibara Hospital (JP)
- National Defense Medical College (JP)
- Nagoya University (JP)
- Nara Medical University (JP)
- Yokohama City University (JP)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-07-04
- DOI
- https://doi.org/10.1161/jaha.124.040252
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 0.00