Investigation of early-stage cardiovascular-kidney-metabolic syndrome on retinal structure and function evaluated by optical coherence tomography angiography
Early-stage CKM syndrome is associated with subtle retinal structural and vascular alterations detectable by OCTA, particularly within the macular layers. OCTA-derived biomarkers, including outer temporal thickness and macular vessel density, may serve as non-invasive tools for evaluating systemic health status, offering promise for the early detection of metabolic and cardiovascular risks.
Authors
- Congbi Liang
- Chubin Ou (ORCID: https://orcid.org/0000-0003-2614-0418)
- Peiqiong Lao
- Zhenyu Liang (ORCID: https://orcid.org/0000-0002-8746-315X)
- Wanhua Li (ORCID: https://orcid.org/0000-0002-2730-0543)
- Jianping Yang (ORCID: https://orcid.org/0000-0001-8715-3090)
- Lin An
- Jingfeng Zhang (ORCID: https://orcid.org/0000-0002-8206-6235)
- Rong Liang (ORCID: https://orcid.org/0000-0002-6419-9464)
- Junhua Zhu
- Yunyi Liang
Institutions
- Foshan University (CN)
- Sun Yat-sen University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Hangzhou Dianzi University (CN)
- Southern Medical University (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-07-04
- DOI
- https://doi.org/10.3389/fmed.2025.1614321
- Primary Topic
- Retinal Imaging and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Planning Project of Guangdong Province