Effects of a kappa opioid receptor antagonist on delayed postoperative pain recovery in a novel mouse sleep disorder model
These findings suggest that sleep disorders, such as those modeled by PAWW, could delay postoperative pain recovery, and that KOR antagonists might provide therapeutic benefits in the management of delayed recovery of postoperative pain induced by sleep disorders.
Authors
- Masaaki Kawakami
- Hisakatsu Ito (ORCID: https://orcid.org/0000-0002-8492-6550)
- Tomonori Takazawa (ORCID: https://orcid.org/0000-0002-0119-3532)
- Masashi Yoshida (ORCID: https://orcid.org/0000-0002-4052-4277)
- S Sugimoto
Institutions
- Toyama University Hospital (JP)
- Gunma University Hospital (JP)
Publication Details
- Journal
- Frontiers in Pain Research
- Published
- 2025-07-04
- DOI
- https://doi.org/10.3389/fpain.2025.1516935
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science