Impact of Terminalia chebula Retz polysaccharide and Rubia cordifolia L. processed Terminalia chebula Retz polysaccharides on cyclophosphamide-induced immunosuppression in Chinese yellow quail
RTCP effectively counteracted CTX-induced immunosuppression by modulating innate and adaptive immunity, including complement activation and Th1/Th2 balance. These findings highlight RTCP's potential as a natural immunomodulator in poultry. Further research should optimize dosing and explore gut-microbiota-immune interactions to enhance therapeutic applications.
Authors
- Min He (ORCID: https://orcid.org/0000-0001-7113-2973)
- Jing Wang (ORCID: https://orcid.org/0009-0006-3929-9267)
- Qiang Wu (ORCID: https://orcid.org/0000-0002-5455-8849)
- T G Tong
Institutions
- Sichuan Agricultural University (CN)
- Yibin University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-07-04
- DOI
- https://doi.org/10.3389/fcimb.2025.1620053
- Primary Topic
- Bioactive Compounds and Antitumor Agents
- Type
- article
- Field-Weighted Citation Impact
- 0.00