GLP-1 and GIP may play a role in long-term weight trajectories after gastric bypass
In sum, greater WR was associated with higher levels of postprandial glucose and GIP, along with lower GLP-1 and glucagon excursions. Whether these are cause or consequence of WR remains to be clarified. Additionally, GIP and GLP-1 profile of participants with T2D relapse did not differ from those with T2D remission.
Authors
- Mariana P. Monteiro (ORCID: https://orcid.org/0000-0002-0662-1831)
- Sofia S. Pereira (ORCID: https://orcid.org/0000-0001-6947-4560)
- Bolette Hartmann (ORCID: https://orcid.org/0000-0001-8509-2036)
- Carolina B. Lobato (ORCID: https://orcid.org/0000-0003-3708-6859)
- Jens J. Holst (ORCID: https://orcid.org/0000-0001-6853-3805)
- Marta Guimarães (ORCID: https://orcid.org/0000-0001-8094-7197)
- Sara Andrade (ORCID: https://orcid.org/0000-0001-9825-2772)
- Mariana Fernandes Machado (ORCID: https://orcid.org/0000-0001-6421-9309)
- Rui F Almeida
- Mário Nora
Institutions
- University of Copenhagen (DK)
- Universidade do Porto (PT)
- Novo Nordisk Foundation (DK)
- Hospital de São Sebastião (PT)
- i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto (PT)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-07-04
- DOI
- https://doi.org/10.3389/fendo.2025.1624001
- Citations
- 3
- Primary Topic
- Bariatric Surgery and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 6.02
Funders
- “la Caixa” Foundation
- Danish Diabetes Academy
- Sociedade Portuguesa De Diabetologia
- Ministerio de Economía y Competitividad
- Novo Nordisk
- Novo Nordisk Fonden
- Novo Nordisk Foundation Center for Basic Metabolic Research
- Fundación Bancaria Caixa d'Estalvis i Pensions de Barcelona
- Fundação para a Ciência e a Tecnologia