LINC00662 regulates osteogenic differentiation of BMSCs and inhibits fracture healing via miR-330-3p/PTEN axis
LINC00662 and miR-330-3p synergistically could improve the diagnostic efficiency of DFH. LINC00662 impedes fracture healing by suppressing osteogenic differentiation and proliferation of HBMSCs while promoting apoptosis in HBMSCs via the miR-330-3p/PTEN axis.
Authors
- Jian Gong (ORCID: https://orcid.org/0000-0002-8793-0328)
- Teng Zeng (ORCID: https://orcid.org/0000-0002-0374-9549)
- Li Zhu (ORCID: https://orcid.org/0000-0001-5249-6536)
- Jie-Hua Luo
- Kun Ding (ORCID: https://orcid.org/0000-0003-1098-5424)
- Huasong Luo (ORCID: https://orcid.org/0009-0000-4580-2996)
- Mohamed Lamin Bangura (ORCID: https://orcid.org/0009-0008-4429-7068)
- Yunfeng Lv
- Jinliang Ma
Institutions
- Harbin Medical University (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Guangzhou Liwan District Traditional Chinese Medicine Hospital (CN)
- Traditional Chinese Medicine Hospital of Kunshan (CN)
- CM Hospital (KR)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- BMC Musculoskeletal Disorders
- Published
- 2025-07-04
- DOI
- https://doi.org/10.1186/s12891-025-08845-z
- Citations
- 1
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.81