Potential Causal Relationship Between Chronic Obstructive Pulmonary Disease and Diabetes: A Bidirectional Two-Sample Mendelian Randomization Study
This study suggested a modest but statistically significant causal association between T2D and COPD in individuals of European ancestry. Further explorations are required to better understand the underlying mechanisms linking diabetes to COPD development.
Authors
- Hongli Jiang (ORCID: https://orcid.org/0000-0001-9262-6112)
- Xinyan Wang (ORCID: https://orcid.org/0000-0002-4126-231X)
- Wei Liu (ORCID: https://orcid.org/0000-0003-1811-9520)
- Xin Chen (ORCID: https://orcid.org/0000-0002-3685-0854)
- Ruizhi Feng
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Zigong First People's Hospital (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- International Journal of COPD
- Published
- 2025-07-01
- DOI
- https://doi.org/10.2147/copd.s516346
- Citations
- 2
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 3.63
Funders
- European Respiratory Society
- National Natural Science Foundation of China