Treatment of pharmacoresistant states in psychiatry. Part 2: Treatment-resistant depression
lnek se sousted na farmakorezistentn depresi a uvd monosti lby, tj. zmnu stvajcho antidepresiva za jin, augmentaci a kombinaci antidepresiv. Detailnji je popsna augmentace prvn (ketamin, esketamin) a druhou generac (esmetadon) nekompetivnch antagonist NMDA receptor s rychlm nstupem antidepresivnho efektu. Dle jsou zmnny nkter ltky, kter byly uvny ped nstupem psychofarmakologick ry (opioidy, psilocybin) a alternativn pstupy (nutraceutika, probiotika), kter maj urit potencil zvan depresivn pznaky zmrnit.
Authors
- Eva Češková (ORCID: https://orcid.org/0000-0002-6626-1057)
Publication Details
- Journal
- Psychiatrie pro praxi
- Published
- 2025-07-04
- DOI
- https://doi.org/10.36290/psy.2025.015
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00