Synthesis, antiproliferative evaluation and <i>in silico</i> studies of new quinazoline derivatives as VEGFR-2 inhibitors
Compounds <b>3i</b> and <b>3j</b> exhibit promising VEGFR-2 inhibitory properties and significant anticancer activity, warranting further investigation.
Authors
- Adel A. Marzouk (ORCID: https://orcid.org/0000-0003-4864-2056)
- İsmail Çeli̇k (ORCID: https://orcid.org/0000-0002-8146-1663)
- Montaser Sh. A. Shaykoon (ORCID: https://orcid.org/0000-0003-4044-9120)
- Ahd A. Mansour (ORCID: https://orcid.org/0000-0003-3729-4770)
- Abdallah M. Alfayomy (ORCID: https://orcid.org/0000-0003-3704-5483)
- Dina A. Bakhotmah (ORCID: https://orcid.org/0000-0001-6651-7932)
- Abdelsalam Mohamed Abdelsalam Ouf (ORCID: https://orcid.org/0000-0002-3794-3403)
- Mohamed Ayman El‐Zahabi (ORCID: https://orcid.org/0000-0003-4538-5840)
- Mariam K. Alamoudi (ORCID: https://orcid.org/0000-0001-7653-0401)
Institutions
- Prince Sattam Bin Abdulaziz University (SA)
- King Abdulaziz University (SA)
- University of Mississippi (US)
- Soliman Fakeeh Hospital (SA)
- Al-Azhar University (ID)
- Erciyes University (TR)
Publication Details
- Journal
- Future Medicinal Chemistry
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1080/17568919.2025.2525073
- Primary Topic
- Quinazolinone synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Development Fund