Distinct Lung Adenocarcinoma-Associated Microbiota Are Associated with Inflammatory Immune Landscapes and Tumor Cell Proliferation via LCIIAR–ISG15 Regulatory Networks
LUAD features a distinctive microbiota that engages with inflammatory and ceRNA regulatory pathways. These observations underscore the value of targeting microbiome-influenced mechanisms, such as the LCIIAR-ISG15 axis, as a promising approach to enhance treatment outcomes in lung adenocarcinoma.
Authors
- S Liu (ORCID: https://orcid.org/0000-0002-3561-7583)
- Zijian Zhang (ORCID: https://orcid.org/0000-0001-6974-3951)
Institutions
- Capital Medical University (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Beijing Chaoyang Emergency Medical Center (CN)
Publication Details
- Journal
- Cancer Management and Research
- Published
- 2025-07-01
- DOI
- https://doi.org/10.2147/cmar.s520098
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52