Real-time cortical activity during virtual reality practice in people with multiple sclerosis: a pilot fNIRS study
While no significant differences in overall cortical activation were found between VR and real-world tasks, pwMS exhibited reduced neurovascular responses compared to healthy controls, indicating impaired adaptability. These findings support VR's feasibility for motor rehabilitation while highlighting the need for further studies on neuroplasticity, cognitive-motor integration, and lesion-related neurovascular changes in pwMS.
Authors
- Tali Drori
- Sapir Dreyer-Alster (ORCID: https://orcid.org/0000-0002-7475-1902)
- Massimiliano Pau (ORCID: https://orcid.org/0000-0001-9835-3629)
- Alon Kalron (ORCID: https://orcid.org/0000-0001-7999-0868)
- Rea Lavi (ORCID: https://orcid.org/0000-0002-0788-7236)
- Eleonora E. Cocco (ORCID: https://orcid.org/0000-0002-3878-8820)
Institutions
- Tel Aviv University (IL)
- University of Cagliari (IT)
- Sheba Medical Center (IL)
Publication Details
- Journal
- Journal of NeuroEngineering and Rehabilitation
- Published
- 2025-07-04
- DOI
- https://doi.org/10.1186/s12984-025-01681-1
- Citations
- 2
- Primary Topic
- Optical Imaging and Spectroscopy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- Ministry of Science and Technology, Israel
- Ministero degli Affari Esteri e della Cooperazione Internazionale