Retention rate of TNF inhibitors versus IL-17 inhibitors in ankylosing spondylitis patients with prior biologics experience

In patients with AS who had prior experience with biologics, the drug retention of TNF inhibitors tended to be higher compared to IL-17 inhibitors in real-world clinical practice. However, the factors significantly associated with higher drug survival were a lower number of previously exposed biologics and a lower BASDAI.

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Publication Details

Journal
Arthritis Research & Therapy
Published
2025-07-04
DOI
https://doi.org/10.1186/s13075-025-03601-z
Citations
2
Primary Topic
Spondyloarthritis Studies and Treatments
Type
article
Field-Weighted Citation Impact
3.34

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article

Retention rate of TNF inhibitors versus IL-17 inhibitors in ankylosing spondylitis patients with prior biologics experience

Bong-Woo Lee, Wan‐Uk Kim, Ji Hyeon Ju, Seung‐Ki Kwok et al.
2 citations
Arthritis Research & Therapy
Spondyloarthritis Studies and Treatments
3.34
article

Retention rate of TNF inhibitors versus IL-17 inhibitors in ankylosing spondylitis patients with prior biologics experience

Bong-Woo Lee, Wan‐Uk Kim, Ji Hyeon Ju, Seung‐Ki Kwok, Jennifer Jooha Lee, Youngjae Park, Ji Won Yang, Sung‐Hwan Park
article en
2 citations

Abstract

In patients with AS who had prior experience with biologics, the drug retention of TNF inhibitors tended to be higher compared to IL-17 inhibitors in real-world clinical practice. However, the factors significantly associated with higher drug survival were a lower number of previously exposed biologics and a lower BASDAI.

Arthritis Research & TherapyVol. 27(1)
The Catholic University of Korea Seoul St. Mary's Hospital (KR), Catholic University of Korea (KR)
National Research Foundation, Catholic University of Korea, National Research Foundation of Korea, Ministry of Science and ICT, South Korea, Seoul St. Mary's Hospital, Catholic University of Korea
Good health and well-being
Openalex Percentile: Top 8%
Spondyloarthritis Studies and Treatments
3.34
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Retention rate of TNF inhibitors versus IL-17 inhibitors in ankylosing spondylitis patients with prior biologics experience — Bong-Woo Lee, Wan‐Uk Kim, et al. · Arthritis Research & Therapy (2025) | TGRS Research Map | TGRS