Association of estimated glucose disposal rate with chronic kidney disease: comparative analysis against traditional insulin resistance indices
The eGDR has emerged as a reliable and practical marker of insulin resistance associated with CKD indicators, demonstrating stronger associations with eGFR and UACR compared to traditional measures like HOMA-IR, QUICKI, TyG, TyG-BMI and TyG-WC. The simplicity of calculating eGDR enhances its utility as a valuable tool for the early detection and management of CKD, potentially improving clinical outcomes.
Authors
- Yuyin Jiang (ORCID: https://orcid.org/0009-0009-9019-1739)
- Wei Tang (ORCID: https://orcid.org/0000-0002-1140-9149)
- Yuanxin Liu (ORCID: https://orcid.org/0000-0002-0673-4887)
- Siyuan Cui (ORCID: https://orcid.org/0009-0003-4787-0206)
- Mingda Liu (ORCID: https://orcid.org/0000-0002-0015-0848)
Institutions
- Nanjing Brain Hospital (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Wuxi People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-07-04
- DOI
- https://doi.org/10.3389/fendo.2025.1507735
- Citations
- 1
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Wuxi Municipal Bureau on Science and Technology