Invasive Mucormycosis in a Chronic Lymphocytic Leukemia Patient on Zanubrutinib: A Case Report

This study presents a case of rapidly progressive mucormycosis co-infected with bacterial and viral pathogens, highlighting the importance of early intervention and accurate diagnosis. Delayed identification of the fungal pathogen significantly hindered timely antifungal intervention, underscoring the importance of appropriate empirical therapies in hematological patients treated with zanubrutinib. Future research should focus on antifungal stewardship and epidemiological surveillance studies to improve early detection and guide targeted empirical treatment for high-risk populations.

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Publication Details

Journal
Infection and Drug Resistance
Published
2025-07-01
DOI
https://doi.org/10.2147/idr.s526660
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
0.00

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article

Invasive Mucormycosis in a Chronic Lymphocytic Leukemia Patient on Zanubrutinib: A Case Report

Qiao‐Li Lv, Hazrat Bilal, Yuan Qiu, Xiaohui Li et al.
Infection and Drug Resistance
Antifungal resistance and susceptibility
article

Invasive Mucormycosis in a Chronic Lymphocytic Leukemia Patient on Zanubrutinib: A Case Report

Qiao‐Li Lv, Hazrat Bilal, Yuan Qiu, Xiaohui Li, Bin Xu, Huizhong Qiu
article en

Abstract

This study presents a case of rapidly progressive mucormycosis co-infected with bacterial and viral pathogens, highlighting the importance of early intervention and accurate diagnosis. Delayed identification of the fungal pathogen significantly hindered timely antifungal intervention, underscoring the importance of appropriate empirical therapies in hematological patients treated with zanubrutinib. Future research should focus on antifungal stewardship and epidemiological surveillance studies to improve early detection and guide targeted empirical treatment for high-risk populations.

Infection and Drug ResistanceVol. Volume 18
First Affiliated Hospital of Jiangxi Medical College (CN), Jiangxi Provincial Cancer Hospital (CN)
Education Department of Jiangxi Province, Health Commission of Jiangxi Province
Zero hunger
Openalex Percentile: Top 80%
Antifungal resistance and susceptibility
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Invasive Mucormycosis in a Chronic Lymphocytic Leukemia Patient on Zanubrutinib: A Case Report — Qiao‐Li Lv, Hazrat Bilal, et al. · Infection and Drug Resistance (2025) | TGRS Research Map | TGRS