Thromboelastography-guided Blood Product Management: A Series of Three Cases

Thromboelastography (TEG) is a diagnostic tool used to assess blood clotting in real time by measuring the viscoelastic properties of blood. It measures the clot’s strength and stability. It provides a comprehensive view of haemostasis, which includes clot formation, strength, and dissolution. This can be useful in clinical settings by guiding transfusion and anticoagulation therapy in various medical conditions. It can be useful in blood product administration for the patient’s specific needs. TEG can help assess the functional capacity of the liver in relation to clotting factor production and the overall coagulation process. In obstetric patients, particularly during labour and complications during delivery, TEG can help manage and predict bleeding risks associated with conditions like preeclampsia or Disseminated Intravascular Coagulation (DIC). Here, we discussed three separate cases (1 male, 2 females) described, each presenting unique clinical scenarios, including those from Intensive Care Unit (ICU) settings. A case of Postpartum Haemorrhage (PPH) with Hemolysis, Elevated Liver enzymes, and Low Platelets (HELLP) syndrome, a case of haemophilia A, and a case of snake bite with signs of envenomation were managed with TEG to guide component-based therapy, based on the specific needs of each patient.