Decoding <scp>PANoptosis</scp> in Gout: Signature Gene Identification and Immune Infiltration Profiling
We identified the hub gene SOCS3 in gout and elucidated its mechanistic roles by integrated bioinformatics analysis, machine learning approach, and clinical validation, providing critical insights for advancing diagnostic biomarkers and therapeutic strategies in gout management.
Authors
- Aifang Li
- Zhen Wu (ORCID: https://orcid.org/0000-0002-3607-6440)
- Junjie Cao (ORCID: https://orcid.org/0000-0003-0484-8167)
- Gan Luo (ORCID: https://orcid.org/0000-0002-3644-5752)
- Yuan Liu (ORCID: https://orcid.org/0009-0007-5944-3913)
Institutions
- Wuhan University (CN)
- Fifth Hospital In Wuhan (CN)
- Xi'an Chest Hospital (CN)
Publication Details
- Journal
- International Journal of Rheumatic Diseases
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1111/1756-185x.70344
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 0.00