Middle Longitudinal Fascicle Maldevelopment on Free Water Corrected MR Diffusion Underlies Language Impairment in Autism
The MdLF exhibits aberrant developmental trajectories in preschool children with ASD, and its microstructural integrity is linked to language impairment. These findings underscore the MdLF's role in ASD-related language deficits and highlight the importance of early neurodevelopmental assessment.
Authors
- Doudou Cao (ORCID: https://orcid.org/0000-0001-6155-606X)
- Zhou Lan (ORCID: https://orcid.org/0000-0001-5881-2827)
- Yi Wang (ORCID: https://orcid.org/0000-0002-4448-1809)
- Fan Zhang (ORCID: https://orcid.org/0000-0002-8736-8961)
- Qi Qi (ORCID: https://orcid.org/0000-0001-9192-8928)
- Wei Zhang (ORCID: https://orcid.org/0000-0002-1218-9475)
- Shijun Li (ORCID: https://orcid.org/0000-0001-8185-0549)
- Li Zhu (ORCID: https://orcid.org/0000-0001-5249-6536)
- Ni Li (ORCID: https://orcid.org/0000-0003-3550-4164)
- Guolin Ma
Institutions
- Harvard University (US)
- University of Electronic Science and Technology of China (CN)
- China-Japan Friendship Hospital (CN)
- Chinese PLA General Hospital (CN)
- Ningxia Medical University (CN)
- Ningxia Medical University General Hospital (CN)
Publication Details
- Journal
- Journal of Neuroimaging
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1111/jon.70067
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Beijing Nova Program
- National Key Research and Development Program of China