The Toxicity of Dimethyl Sulfoxide Combined with the Alkylating Agent MNU on Mice: Focusing on Mortality and Activity Impairment
DMSO has certain toxicity, and when combined with alkylating agents such as MNU, it can lead to reduced activity and an increased mortality rate in mice. It is recommended to closely monitor the mice during the use of such reagents and to establish appropriate research observation protocols.
Authors
- Qiurui He (ORCID: https://orcid.org/0000-0002-9676-2311)
- Weiming Yan (ORCID: https://orcid.org/0000-0003-2636-7313)
- Xiao Lin (ORCID: https://orcid.org/0000-0002-4255-2693)
- Yuxin Xia (ORCID: https://orcid.org/0000-0003-0150-5273)
- Xiangrong Zheng (ORCID: https://orcid.org/0000-0002-8616-0499)
- Xiaohong Zhang (ORCID: https://orcid.org/0000-0003-3760-6121)
Institutions
- Fujian Medical University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-07-01
- DOI
- https://doi.org/10.2147/dddt.s521506
- Citations
- 1
- Primary Topic
- Morinda citrifolia extract uses
- Type
- article
- Field-Weighted Citation Impact
- 2.38
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Fujian Province
- Fuzhou General Hospital