Evaluation of colistin susceptibility by four phenotypic methods compared to broth microdilution in multidrug-resistant Klebsiella pneumoniae

This study highlights the benefits of alternative phenotypic methods compared to reference BMD for assessing colistin susceptibility, including ease of use, cost-effectiveness, and rapid results. Our findings emphasize the need for more comprehensive multicenter studies to validate and improve these methods, especially those with more isolates with MIC values near the breakpoint.

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Publication Details

Journal
BMC Microbiology
Published
2025-07-05
DOI
https://doi.org/10.1186/s12866-025-04121-1
Citations
3
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
1.77
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article

Evaluation of colistin susceptibility by four phenotypic methods compared to broth microdilution in multidrug-resistant Klebsiella pneumoniae

Sinem Kaya, Göksun Karaman, Tuğrul Hoşbul, Hasan Karakuş et al.
3 citations
BMC Microbiology
Antibiotic Resistance in Bacteria
1.77
article

Evaluation of colistin susceptibility by four phenotypic methods compared to broth microdilution in multidrug-resistant Klebsiella pneumoniae

Sinem Kaya, Göksun Karaman, Tuğrul Hoşbul, Hasan Karakuş, Ilgaz Kazaz
article en
3 citations

Abstract

This study highlights the benefits of alternative phenotypic methods compared to reference BMD for assessing colistin susceptibility, including ease of use, cost-effectiveness, and rapid results. Our findings emphasize the need for more comprehensive multicenter studies to validate and improve these methods, especially those with more isolates with MIC values near the breakpoint.

BMC MicrobiologyVol. 25(1)
University of Health Science (KH), Gülhane Askerî Tıp Akademisi (TR), Sağlık Bilimleri Üniversitesi (TR), University of Health Sciences Antigua (AG)
Zero hunger
Openalex Percentile: Top 15%
Antibiotic Resistance in Bacteria
1.77
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Evaluation of colistin susceptibility by four phenotypic methods compared to broth microdilution in multidrug-resistant Klebsiella pneumoniae — Sinem Kaya, Göksun Karaman, et al. · BMC Microbiology (2025) | TGRS Research Map | TGRS