Modeling Clinical Data with Attention: A Knowledge Graph Approach with CliniKG

Given a set of historical, unlabeled patient records, how can we model the relationships between various concepts related to health conditions and treatments? Modeling health data as knowledge graphs can aid in better understanding and mining recurrent and abnormal patterns within massive amounts of records. However, for generic data modeling, the concepts and relationships of the data are often defined manually, which can be laborious and prone to human errors. The lack of structure in textual reports makes modeling challenging, as there is typically no standard in information, terminology, or other elements. This work proposes CliniKG for utilizing Large Language Models (LLMs) to structure patient records, enabling the modeling of health data concepts. First, we employ LLMs with zero-, or few-shot learning to define the graph's relationships of pairwise concepts. Based on the resulting modeling, we extract meaningful features from nodes and define their semantics automatically. With data visualizations, CliniKG highlights key findings, such as recurrent or rare relationships. The experimental evaluation shows CliniKG in action using a real dataset from a public hospital in Brazil. We performed a qualitative analysis with 40 domain experts to evaluate medium-sized LLMs and prompt con-figurations. The study reveals interesting patterns automatically identified within the data. CliniKG exhibits linear performance relative to the number of nodes, and the visual tools can assist specialists in monitoring patients' conditions.

Authors

Institutions

Publication Details

Published
2025-06-18
DOI
https://doi.org/10.1109/cbms65348.2025.00156
Primary Topic
Biomedical Text Mining and Ontologies
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Modeling Clinical Data with Attention: A Knowledge Graph Approach with CliniKG

Agma J. M. Traina, Mauro Marcel Olivatto, Marco A. Gutiérrez, É Moura et al.
Biomedical Text Mining and Ontologies
article

Modeling Clinical Data with Attention: A Knowledge Graph Approach with CliniKG

Agma J. M. Traina, Mauro Marcel Olivatto, Marco A. Gutiérrez, É Moura, Leonardo O. Campos, Rafael C. G. Conrado
article en

Abstract

Given a set of historical, unlabeled patient records, how can we model the relationships between various concepts related to health conditions and treatments? Modeling health data as knowledge graphs can aid in better understanding and mining recurrent and abnormal patterns within massive amounts of records. However, for generic data modeling, the concepts and relationships of the data are often defined manually, which can be laborious and prone to human errors. The lack of structure in textual reports makes modeling challenging, as there is typically no standard in information, terminology, or other elements. This work proposes CliniKG for utilizing Large Language Models (LLMs) to structure patient records, enabling the modeling of health data concepts. First, we employ LLMs with zero-, or few-shot learning to define the graph's relationships of pairwise concepts. Based on the resulting modeling, we extract meaningful features from nodes and define their semantics automatically. With data visualizations, CliniKG highlights key findings, such as recurrent or rare relationships. The experimental evaluation shows CliniKG in action using a real dataset from a public hospital in Brazil. We performed a qualitative analysis with 40 domain experts to evaluate medium-sized LLMs and prompt con-figurations. The study reveals interesting patterns automatically identified within the data. CliniKG exhibits linear performance relative to the number of nodes, and the visual tools can assist specialists in monitoring patients' conditions.

Universidade de Ribeirão Preto (BR), Universidade Federal da Fronteira Sul (BR)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Openalex Percentile: Top 85%
Biomedical Text Mining and Ontologies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Modeling Clinical Data with Attention: A Knowledge Graph Approach with CliniKG — Agma J. M. Traina, Mauro Marcel Olivatto, et al. · (2025) | TGRS Research Map | TGRS