Clinical Cases in the Diagnosis of Cardiac Sarcoidosis

The clinical presentation of cardiac sarcoidosis is often nonspecific and overlaps with other conditions, making the diagnosis challenging. Differences exist in diagnostic guidelines across major consensus statements. Although tissue biopsy is the gold standard, the yield of endomyocardial biopsy is low due to its focal distribution in the myocardium and difficulty of the procedure. We describe 4 cases of cardiac sarcoidosis to illustrate the important concepts of diagnosis of this condition.

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Publication Details

Journal
JACC Case Reports
Published
2025-07-01
DOI
https://doi.org/10.1016/j.jaccas.2025.103686
Primary Topic
Sarcoidosis and Beryllium Toxicity Research
Type
article
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article

Clinical Cases in the Diagnosis of Cardiac Sarcoidosis

Jennifer Maning, Richard L. Weinberg, Ike Stanley Okwuosa, Raymond Goodwin et al.
JACC Case Reports
Sarcoidosis and Beryllium Toxicity Research
article

Clinical Cases in the Diagnosis of Cardiac Sarcoidosis

Jennifer Maning, Richard L. Weinberg, Ike Stanley Okwuosa, Raymond Goodwin, Paul C Cremer, Chun Yuan Khoo, Susan Russell, Peter H. S. Sporn, Hatice Savas, Susan Lehrer, Ryan Avery
article en

Abstract

The clinical presentation of cardiac sarcoidosis is often nonspecific and overlaps with other conditions, making the diagnosis challenging. Differences exist in diagnostic guidelines across major consensus statements. Although tissue biopsy is the gold standard, the yield of endomyocardial biopsy is low due to its focal distribution in the myocardium and difficulty of the procedure. We describe 4 cases of cardiac sarcoidosis to illustrate the important concepts of diagnosis of this condition.

JACC Case ReportsVol. 30(17)
Northwestern Memorial Hospital (US)
Good health and well-being
Openalex Percentile: Top 79%
Sarcoidosis and Beryllium Toxicity Research
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Clinical Cases in the Diagnosis of Cardiac Sarcoidosis — Jennifer Maning, Richard L. Weinberg, et al. · JACC Case Reports (2025) | TGRS Research Map | TGRS