13N-Ammonia PET Can Visualize Improvement of the Left Ventricular MFR by Transcatheter Pulmonary Valve Implantation
The patient was a woman with repaired tetralogy of Fallot. Cardiac magnetic resonance revealed right ventricular enlargement and severe pulmonary regurgitation, and we performed a transcatheter pulmonary valve implantation. Preoperative <sup>13</sup>N-ammonia positron emission tomography indicated myocardial flow reserve (MFR) was reduced, but postoperative MFR improved to within the normal range. The increased forward flow due to pulmonary regurgitation improvement may have increased the output; the improved left-right ventricular interaction due to decreasing right ventricular load and volume reduction may have contributed to the increase in MFR. These findings indicate <sup>13</sup>N-ammonia positron emission tomography visualizes MFR improvements by transcatheter pulmonary valve implantation.
Authors
- Tomohito Kogure (ORCID: https://orcid.org/0000-0001-8956-9698)
- Atsushi Yamamoto (ORCID: https://orcid.org/0000-0003-3020-260X)
- Junichi Yamaguchi (ORCID: https://orcid.org/0000-0003-0967-0978)
- Michinobu Nagao (ORCID: https://orcid.org/0000-0001-6049-8857)
Institutions
- Tokyo Women's Medical University (JP)
Publication Details
- Journal
- JACC Case Reports
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1016/j.jaccas.2025.103794
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00