Tumor sink effect in PSMA-targeted theranostics: intra-patient evaluation of a cohort receiving 225Ac/177Lu-PSMA tandem radioligand therapy
This analysis demonstrates the presence of the TSE in mCRPC patients undergoing the innovative <sup>225</sup>Ac/<sup>177</sup>Lu-PSMA tandem radioligand therapy concept. TSE may hold significant clinical implications and may play a role towards more individualized RLT.
Authors
- Caroline Burgard (ORCID: https://orcid.org/0000-0003-1522-8860)
- Arne Blickle (ORCID: https://orcid.org/0009-0009-2460-7249)
- Samer Ezziddin (ORCID: https://orcid.org/0000-0003-4110-3375)
- Sven Petto
- Mark Bartholomä (ORCID: https://orcid.org/0000-0002-0361-2833)
- Stephan Maus (ORCID: https://orcid.org/0000-0002-5131-526X)
- Andrea Schaefer-Schuler (ORCID: https://orcid.org/0000-0002-2439-5786)
- Florian Rosar (ORCID: https://orcid.org/0000-0002-2985-4099)
- Marie D Muenzenberg
Institutions
- Saarland University (DE)
Publication Details
- Journal
- The Quarterly Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-07-01
- DOI
- https://doi.org/10.23736/s1824-4785.25.03627-1
- Citations
- 1
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 1.52