Dengue cerebellitis in middle childhood from South India

We had a girl in middle childhood, who presented with fever of 7 days duration, vomiting, abdominal pain, headache, myalgia and arthralgia. The child was conscious with signs of shock. With the provisional diagnosis of dengue fever, enteric fever or scrub typhus, the child was given all supportive management. Lab investigations covering the fever panel were sent. Within 24 hours of admission, the child developed horizontal nystagmus, diplopia and intermittent dizziness. Fundus examination showed papilloedema. MRI brain showed hyperintensity of the cerebellum in T2 sections suggestive of cerebellitis. Dengue IgM antibody was positive with transaminitis and hyperferritinaemia. Child was given anti-oedema measures with supportive care. The patient recovered on day 10 of illness, and cerebellar signs subsided. Though dengue fever is commonly seen in tropical countries, the atypical presentation in the form of cerebellitis is found to be rare. The timely diagnosis helped in rapid recovery from this neurological manifestation.

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Publication Details

Journal
BMJ Case Reports
Published
2025-07-01
DOI
https://doi.org/10.1136/bcr-2025-266437
Primary Topic
Mosquito-borne diseases and control
Type
article
Field-Weighted Citation Impact
0.00
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article

Dengue cerebellitis in middle childhood from South India

Sarala Premkumar, Elayaraja Sivaprakasam, Swathi Ganesan, Venkatesh Kumar Balan
BMJ Case Reports
Mosquito-borne diseases and control
article

Dengue cerebellitis in middle childhood from South India

Sarala Premkumar, Elayaraja Sivaprakasam, Swathi Ganesan, Venkatesh Kumar Balan
article en

Abstract

We had a girl in middle childhood, who presented with fever of 7 days duration, vomiting, abdominal pain, headache, myalgia and arthralgia. The child was conscious with signs of shock. With the provisional diagnosis of dengue fever, enteric fever or scrub typhus, the child was given all supportive management. Lab investigations covering the fever panel were sent. Within 24 hours of admission, the child developed horizontal nystagmus, diplopia and intermittent dizziness. Fundus examination showed papilloedema. MRI brain showed hyperintensity of the cerebellum in T2 sections suggestive of cerebellitis. Dengue IgM antibody was positive with transaminitis and hyperferritinaemia. Child was given anti-oedema measures with supportive care. The patient recovered on day 10 of illness, and cerebellar signs subsided. Though dengue fever is commonly seen in tropical countries, the atypical presentation in the form of cerebellitis is found to be rare. The timely diagnosis helped in rapid recovery from this neurological manifestation.

BMJ Case ReportsVol. 18(7)
Sri Ramachandra Institute of Higher Education and Research (IN)
Good health and well-being
Openalex Percentile: Top 77%
Mosquito-borne diseases and control
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