Association of Reduced Brain Metabolism With Motor Function and Survival in Amyotrophic Lateral Sclerosis Patients With Neurofilament Heavy (<scp>NEFH</scp>) Gene Mutation
Reduced brain glucose metabolism in the cortex-striatum/limbic system-brainstem circuit may potentially serve as an independent prognostic factor for patients with ALS and NEFH mutation.
Authors
- Xiaoping Yi (ORCID: https://orcid.org/0000-0002-4220-1981)
- Yuanchao Zhang (ORCID: https://orcid.org/0000-0001-8191-4899)
- Alessandro Grecucci (ORCID: https://orcid.org/0000-0001-6043-2196)
- Bihong T. Chen (ORCID: https://orcid.org/0000-0002-3127-0711)
- Ziqin Liu
- Fan Hu (ORCID: https://orcid.org/0000-0002-0522-392X)
- Renshi Xu (ORCID: https://orcid.org/0000-0003-0313-3434)
- Pan Liu (ORCID: https://orcid.org/0000-0001-9222-0323)
- Xueying Wang (ORCID: https://orcid.org/0000-0001-9291-793X)
- Junling Wang (ORCID: https://orcid.org/0000-0001-5117-5204)
- Wenfeng Cao (ORCID: https://orcid.org/0000-0001-6169-4577)
- Xinyu Song (ORCID: https://orcid.org/0009-0005-6521-9868)
- Jiping Yi (ORCID: https://orcid.org/0009-0008-0465-039X)
Institutions
- City Of Hope National Medical Center (US)
- Central South University (CN)
- University of Electronic Science and Technology of China (CN)
- Chongqing University (CN)
- University of Trento (IT)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Jiangxi Provincial People's Hospital (CN)
- Chenzhou First People's Hospital (CN)
- Xiangya Hospital Central South University (CN)
- Xiangnan University (CN)
- Chongqing Three Gorges University (CN)
- Arizona State University (US)
- University of South China (CN)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1111/ene.70261
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Hunan Province
- National Key Research and Development Program of China
- Fundamental Research Funds for Central Universities of the Central South University