Protective Effect of Lycopene on Ifosfamide-Induced Mitophagy through <i>Pink, Parkin,</i> and <i>LC3-I/II</i> Pathway in Testicular Tissue.

These results underscore lycopene's role as a potent protective agent that can mitigate IFO-induced mitophagy in testicular tissue. Further research into the underlying mechanisms of lycopene's protective effects will be crucial for developing therapeutic strategies to preserve male fertility during IFO treatment.

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Publication Details

Journal
PubMed
Published
2025-05-14
DOI
https://doi.org/10.22074/ijfs.2024.2036627.1740
Primary Topic
Chemotherapy-induced organ toxicity mitigation
Type
article
Field-Weighted Citation Impact
0.00

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article

Protective Effect of Lycopene on Ifosfamide-Induced Mitophagy through Pink, Parkin, and LC3-I/II Pathway in Testicular Tissue.

Ali Thoulfikar A. Imeer, Saeid Abedi, Mohammad Ali Rad
PubMed
Chemotherapy-induced organ toxicity mitigation
article

Protective Effect of Lycopene on Ifosfamide-Induced Mitophagy through Pink, Parkin, and LC3-I/II Pathway in Testicular Tissue.

Ali Thoulfikar A. Imeer, Saeid Abedi, Mohammad Ali Rad
article en

Abstract

These results underscore lycopene's role as a potent protective agent that can mitigate IFO-induced mitophagy in testicular tissue. Further research into the underlying mechanisms of lycopene's protective effects will be crucial for developing therapeutic strategies to preserve male fertility during IFO treatment.

PubMedVol. 19(3)
University of Kerbala (IQ)
Rudi Schulte Research Institute
Openalex Percentile: Top 76%
Chemotherapy-induced organ toxicity mitigation
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