Immunohistochemical Expression of IRE1 and PERK in Breast Cancer: Associations With Clinicopathological Characteristics and Survival Outcomes
High IRE1 and PERK expression levels are associated with aggressive tumor characteristics and reduced survival in breast cancer, underscoring the importance of the unfolded protein response in carcinogenesis and disease progression.
Authors
- Effrosyni Styliara (ORCID: https://orcid.org/0000-0002-1615-7518)
- Georgia Margioula‐Siarkou (ORCID: https://orcid.org/0000-0003-2337-6484)
- Minas Paschopoulos (ORCID: https://orcid.org/0000-0003-1431-8899)
- Stamatios Petousis (ORCID: https://orcid.org/0000-0002-5564-0406)
- Konstantinos D. Dinas (ORCID: https://orcid.org/0000-0001-7144-2840)
- Christos V. Chalitsios (ORCID: https://orcid.org/0000-0002-0836-9385)
- Nikolaos Tsiaras
- Georgios Markozannes (ORCID: https://orcid.org/0000-0001-8481-579X)
- Iordanis Navrozoglou (ORCID: https://orcid.org/0000-0001-9274-4266)
- Stefanos Flindris (ORCID: https://orcid.org/0000-0002-2361-3470)
- Konstantinos Flindris (ORCID: https://orcid.org/0009-0001-9234-5430)
- Chrysoula Margioula‐Siarkou
- Eleni Sakellariou
Institutions
- University of Ioannina (GR)
- Aristotle University of Thessaloniki (GR)
- General Hospital of Ioannina G. Hatzikosta (GR)
- Ippokrateio General Hospital of Thessaloniki (GR)
- University Hospital of Ioannina (GR)
Publication Details
- Journal
- Cancer Diagnosis & Prognosis
- Published
- 2025-07-01
- DOI
- https://doi.org/10.21873/cdp.10466
- Citations
- 1
- Primary Topic
- Cancer Treatment and Pharmacology
- Type
- article
- Field-Weighted Citation Impact
- 1.05