The Effect of Acylcarnitines on Cognitive Function: A Two‐Sample Mendelian Randomization Study
Our results suggest a causal association between acetyl-L-carnitine and butyrylcarnitine levels and adverse neurocognitive effects. Multicenter, multiregional, and large sample studies are needed to further validate these findings.
Authors
- Jianbo Zhou (ORCID: https://orcid.org/0000-0003-2507-9192)
- Sisi Luan (ORCID: https://orcid.org/0000-0002-9144-9537)
- Chenglong Wang (ORCID: https://orcid.org/0000-0002-3567-5759)
- Ziqi Wang (ORCID: https://orcid.org/0009-0007-6701-5177)
- Jinyan Zhang (ORCID: https://orcid.org/0009-0001-2001-1773)
Institutions
- Beijing Tongren Hospital (CN)
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1002/brb3.70646
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China