Clinical and biochemical profile among Indian patients with primary hyperparathyroidism

Clinical and biochemical profile among Indian patients with primary hyperparathyroidism. Hence, a study was conducted from 2022 to 2024 at Mahatma Gandhi Medical College and Hospital, Jaipur, involving 100 patients diagnosed with primary hyperparathyroidism (PHPT). The mean age was 53.2±14.5 years, with a female predominance (69%). Of all patients, 49% were asymptomatic and 51% were symptomatic, with slightly higher mean age in asymptomatic individuals. Biochemically, the mean corrected serum calcium was 12.2±1.6 mg/dl and mean serum parathyroid hormone was 408.9±525.8 pg/ml. A high proportion of asymptomatic cases may reflect improved nutritional status and routine serum calcium screening, highlighting the evolving clinical profile of PHPT.