Sodium-glucose cotransporter-1 inhibition and depression: A Mendelian randomization study
The findings of this Mendelian randomization study indicate that sodium-glucose cotransporter-1 inhibition may decrease the risk of depression in the European population. Future studies must be done to clarify the mechanisms that underlie the causal relationship. Our study provides clear evidence of the potential benefits of sodium-glucose cotransporter-1 inhibition in depression.
Authors
- Gang Fan (ORCID: https://orcid.org/0000-0002-6616-3916)
- Li Jiang (ORCID: https://orcid.org/0000-0002-2647-0380)
- Hong Zuo
- Xun Shi (ORCID: https://orcid.org/0000-0002-8086-6407)
Institutions
- Xian Yang Central Hospital (CN)
- The Eighth Hospital of Xi'an (CN)
- Shaanxi University of Chinese Medicine (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- SAGE Open Medicine
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1177/20503121251352618
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00