INORGANIC COATINGS FOR IMPLANTS IN CARDIOVASCULAR SURGERY: CURRENT STATE OF THE ART (A REVIEW ARTICLE)
Highlights Cardiovascular diseases remain the leading cause of mortality worldwide, driving demand for effective implantable devices (stents, valves, vascular prostheses). Inorganic coatings play a pivotal role in enhancing implant biocompatibility, antithrombogenic properties, and long-term durability. This literature review critically examines both advantages and limitations of inorganic coatings for cardiovascular implants. Abstract Cardiovascular implants such as stents, valves, and vascular prostheses require continuous improvement to enhance their durability and biocompatibility. This review examines contemporary inorganic coatings, including titanium nitride, metal oxides, and diamond-like carbon coatings, which demonstrate potential for improving implant hemocompatibility. Particular focus is given to their role in preventing thrombosis, restenosis, and calcification. The paper analyzes both experimental and clinical data supporting the efficacy of these coatings.
Authors
- A.G. Makaev (ORCID: https://orcid.org/0000-0002-0678-1026)
- Ya. M. Smirnov (ORCID: https://orcid.org/0009-0000-2435-9868)
- М. А. Суровцева (ORCID: https://orcid.org/0000-0002-4752-988X)
- A.S. Grenadyorov (ORCID: https://orcid.org/0000-0001-6013-0200)
- Д. С. Хван (ORCID: https://orcid.org/0000-0002-5925-2275)
- A.V. Protopopov (ORCID: https://orcid.org/0000-0002-2617-2447)
- Д. А. Сирота (ORCID: https://orcid.org/0000-0002-9940-3541)
- M.O. Zhulkov (ORCID: https://orcid.org/0000-0001-7976-596X)
Institutions
- Novosibirsk State Medical University (RU)
- Ministry of Health of the Russian Federation (RU)
- Meshalkin National Medical Research Center (RU)
- Institute of High Current Electronics (RU)
Publication Details
- Journal
- Complex Issues of Cardiovascular Diseases
- Published
- 2025-07-01
- DOI
- https://doi.org/10.17802/2306-1278-2025-14-3-192-202
- Primary Topic
- Orthopaedic implants and arthroplasty
- Type
- article
- Field-Weighted Citation Impact
- 0.00