Thioridazine Induced Bilateral Angle Closure and Myopic Shift

Drug induced angle closure is a sight threatening complication in ophthalmology which if not treated urgently can lead to perpetual vision loss. Identifying the cause of disease and timely intervention can prevent permanent damage to the eye. This case report presents a case and subsequent discussion on thioridazine induced angle closure along with transient myopia. Oral and topical pressure lowering drugs were prescribed which included oral acetazolamide 250mg QID, topical timolol, dorzolamide and brimonidine. This case report highlights some of the key issues pertaining to drug induce angle closure and the potential approach to tackling it. Keywords: Thioridazine, Secondary Angle Closure, Myopia.

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Publication Details

Journal
Pakistan Journal of Ophthalmology
Published
2025-07-01
DOI
https://doi.org/10.36351/pjo.v41i3.1960
Primary Topic
Phenothiazines and Benzothiazines Synthesis and Activities
Type
article
Field-Weighted Citation Impact
0.00
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article

Thioridazine Induced Bilateral Angle Closure and Myopic Shift

Sohail Zia, Laiba Tabassum, Aneeq Ullah Baig Mirza
Pakistan Journal of Ophthalmology
Phenothiazines and Benzothiazines Synthesis and Activities
article

Thioridazine Induced Bilateral Angle Closure and Myopic Shift

Sohail Zia, Laiba Tabassum, Aneeq Ullah Baig Mirza
article en

Abstract

Drug induced angle closure is a sight threatening complication in ophthalmology which if not treated urgently can lead to perpetual vision loss. Identifying the cause of disease and timely intervention can prevent permanent damage to the eye. This case report presents a case and subsequent discussion on thioridazine induced angle closure along with transient myopia. Oral and topical pressure lowering drugs were prescribed which included oral acetazolamide 250mg QID, topical timolol, dorzolamide and brimonidine. This case report highlights some of the key issues pertaining to drug induce angle closure and the potential approach to tackling it. Keywords: Thioridazine, Secondary Angle Closure, Myopia.

Pakistan Journal of OphthalmologyVol. 41(3)
Openalex Percentile: Top 86%
Phenothiazines and Benzothiazines Synthesis and Activities
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