Retrospective Analysis of the Timing of Radiotherapy Intervention After Induction Chemoimmunotherapy in Unresectable Locally Advanced Lung Squamous Cell Carcinoma
Induction chemoimmunotherapy followed by radiotherapy demonstrates promising efficacy and manageable toxicity in unresectable LA-LUSC. Initiating radiotherapy earlier (after 2-3 induction cycles) improves PFS and LPFS and is an independent favorable prognostic factor. Consolidation ICI after combined chemoimmunotherapy and radiotherapy further extends OS compared to induction ICI alone.
Authors
- Li Zeng (ORCID: https://orcid.org/0000-0003-3720-5168)
- Ao Zeng
- Liang Yu (ORCID: https://orcid.org/0009-0007-3922-3454)
- Daiyuan Ma (ORCID: https://orcid.org/0000-0002-0757-9487)
Institutions
- Affiliated Hospital of North Sichuan Medical College (CN)
Publication Details
- Journal
- Cancer Management and Research
- Published
- 2025-07-01
- DOI
- https://doi.org/10.2147/cmar.s517837
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00