Zhongfeng Xingnao Liquid Ameliorated the Early Impairment of Intracerebral Hemorrhage by Inhibiting NF-κB/NLRP3 Axis in Rats
ZFXN emerges as a promising neuroprotective agent for ICH through targeted inhibition of the NF-κB/NLRP3 inflammatory axis, demonstrating optimal efficacy within the critical 6-hour hyperacute phase by mitigating secondary neuroinflammation and addressing current therapeutic gaps in ICH management.
Authors
- Haiyun Yang (ORCID: https://orcid.org/0000-0001-6725-0184)
- Jiafu Guo (ORCID: https://orcid.org/0000-0002-8949-4099)
- Yifan Du
- Shijun Xu (ORCID: https://orcid.org/0000-0002-7454-0873)
- Baoming Luo (ORCID: https://orcid.org/0000-0002-2331-5713)
- Ping Wang (ORCID: https://orcid.org/0000-0002-1557-0394)
- Shiqi Zhang (ORCID: https://orcid.org/0000-0001-9751-7652)
- Yuan Dai (ORCID: https://orcid.org/0009-0001-6017-4956)
- Yun Lu (ORCID: https://orcid.org/0009-0004-1881-3760)
Institutions
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-07-01
- DOI
- https://doi.org/10.2147/jir.s528358
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00