Comparative evaluation of antibacterial property, pH, and drug release of calcium hydroxide-loaded nanoparticles as intracanal medicament – In vitro study
NP incorporation significantly improved the antibacterial efficacy, pH stability, and drug release of Ca(OH)<sub>2</sub>. Chitosan enhanced antimicrobial activity and pH, while PLGA provided superior sustained release. These formulations show potential as advanced intracanal medicaments.
Authors
- S. R. Srinidhi
- Rutuja Patil (ORCID: https://orcid.org/0009-0006-5499-4401)
- Ganesh Jadhav (ORCID: https://orcid.org/0000-0002-3333-2437)
- Vamshi Krishna Humnabad (ORCID: https://orcid.org/0009-0006-0206-8529)
- Ajit Hindlekar (ORCID: https://orcid.org/0000-0001-5966-5304)
- Adapa Sri Shivapriya
Institutions
- All India Institute of Medical Sciences Raipur (IN)
- Dr. D.Y. Patil Vidyapeeth, Pune (IN)
- All India Institute of Medical Sciences Bhopal (IN)
- Dr D Y Patil Dental College & Hospital (IN)
- All India Institute of Medical Sciences, Nagpur (IN)
Publication Details
- Journal
- Journal of Conservative Dentistry and Endodontics
- Published
- 2025-07-01
- DOI
- https://doi.org/10.4103/jcde.jcde_310_25
- Citations
- 4
- Primary Topic
- Endodontics and Root Canal Treatments
- Type
- article
- Field-Weighted Citation Impact
- 7.16