Langerhans cell histiocytosis in an adult patient: rare clinical case in the mandible, with 10-year follow-up

Introduction: Langerhans cell histiocytosis (LCH) is characterized by the infiltration and proliferation of dendritic cells, characterized by normal Langerhans cells. LCH has a widely variable clinical presentation, from a single, mildly aggressive lesion to a multisystemic disease. It is a rare disease, with an incidence of approximately 1 in 2 million individuals, which mainly affects young adults. In general, conservative treatment has good prognosis; however, specific cases may require more radical treatments. Case report: A 35-year-old patient presented with a pathological fracture in...

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Publication Details

Journal
Journal of the Brazilian College of Oral and Maxillofacial Surgery
Published
2025-07-01
DOI
https://doi.org/10.14436/2358-2782.11.2.e252530.oar
Primary Topic
Histiocytic Disorders and Treatments
Type
article
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article

Langerhans cell histiocytosis in an adult patient: rare clinical case in the mandible, with 10-year follow-up

Émerson Filipe de Carvalho Nogueira, Airton Leite Segundo
Journal of the Brazilian College of Oral and Maxillofacial Surgery
Histiocytic Disorders and Treatments
article

Langerhans cell histiocytosis in an adult patient: rare clinical case in the mandible, with 10-year follow-up

Émerson Filipe de Carvalho Nogueira, Airton Leite Segundo
article en

Abstract

Introduction: Langerhans cell histiocytosis (LCH) is characterized by the infiltration and proliferation of dendritic cells, characterized by normal Langerhans cells. LCH has a widely variable clinical presentation, from a single, mildly aggressive lesion to a multisystemic disease. It is a rare disease, with an incidence of approximately 1 in 2 million individuals, which mainly affects young adults. In general, conservative treatment has good prognosis; however, specific cases may require more radical treatments. Case report: A 35-year-old patient presented with a pathological fracture in...

Journal of the Brazilian College of Oral and Maxillofacial SurgeryVol. 11(2)
Openalex Percentile: Top 79%
Histiocytic Disorders and Treatments
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