Renal Barocrinology: The Interface between Obesity and Kidney Health

Obesity is been acknowledged to be a major risk factor for chronic kidney disease (CKD), contributing to both its onset and progression. Over past few decades, the obesity epidemic has lead to an increased incidence of obesityrelated nephropathy, characterised by glomerular hyperfiltration, hypertrophy, and progressive glomerulosclerosis. This review highlights the need for multidisciplinary action to prevent and manage obesityrelated nephropathy. We reiterate the current necessity of routine kidney function screening in people with obesity. We also propose an integrated concept of Renal Barocrinology. This will focus on early screening and preventive strategies, mitigating long-term burden of CKD and its complications, and improving patient outcomes through a collaborative approach.

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Journal
Journal of the Pakistan Medical Association
Published
2025-07-01
DOI
https://doi.org/10.47391/jpma.25-56
Primary Topic
Blood Pressure and Hypertension Studies
Type
article
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article

Renal Barocrinology: The Interface between Obesity and Kidney Health

Nitin Kapoor, Sabine Karam, Sourabh Sharma, Sanjay Kalra
Journal of the Pakistan Medical Association
Blood Pressure and Hypertension Studies
article

Renal Barocrinology: The Interface between Obesity and Kidney Health

Nitin Kapoor, Sabine Karam, Sourabh Sharma, Sanjay Kalra
article en

Abstract

Obesity is been acknowledged to be a major risk factor for chronic kidney disease (CKD), contributing to both its onset and progression. Over past few decades, the obesity epidemic has lead to an increased incidence of obesityrelated nephropathy, characterised by glomerular hyperfiltration, hypertrophy, and progressive glomerulosclerosis. This review highlights the need for multidisciplinary action to prevent and manage obesityrelated nephropathy. We reiterate the current necessity of routine kidney function screening in people with obesity. We also propose an integrated concept of Renal Barocrinology. This will focus on early screening and preventive strategies, mitigating long-term burden of CKD and its complications, and improving patient outcomes through a collaborative approach.

Journal of the Pakistan Medical AssociationVol. 75(07)
Chandigarh University (IN), University of Minnesota (US), Baker Heart and Diabetes Institute (AU), Christian Medical College, Vellore (IN)
Openalex Percentile: Top 73%
Blood Pressure and Hypertension Studies
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Renal Barocrinology: The Interface between Obesity and Kidney Health — Nitin Kapoor, Sabine Karam, et al. · Journal of the Pakistan Medical Association (2025) | TGRS Research Map | TGRS