A MATLAB-Based Solver for Modeling Neurons

We present a Matlab-based cable solver that can be used in place of the existing NEURON platform. The Matlab-based solver provides a transparent alternative to the NEURON solvers that developers can easily modify and integrate for modeling complex scenarios without the need to conform to the NEURON format. We benchmark our solver by modeling a neuron consisting of morphologically distinct components and ion channels inhomogeneously distributed across the neuron membrane regulating its excitability through different mechanisms. We present results on a realistic rat L2/3 pyramidal neuron model and show their agreement with the NEURON solver.

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Publication Details

Published
2025-05-18
DOI
https://doi.org/10.23919/aces66556.2025.11052467
Primary Topic
Neural Networks and Applications
Type
article
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article

A MATLAB-Based Solver for Modeling Neurons

Luis J. Gomez, Vanine Sabino
Neural Networks and Applications
article

A MATLAB-Based Solver for Modeling Neurons

Luis J. Gomez, Vanine Sabino
article en

Abstract

We present a Matlab-based cable solver that can be used in place of the existing NEURON platform. The Matlab-based solver provides a transparent alternative to the NEURON solvers that developers can easily modify and integrate for modeling complex scenarios without the need to conform to the NEURON format. We benchmark our solver by modeling a neuron consisting of morphologically distinct components and ion channels inhomogeneously distributed across the neuron membrane regulating its excitability through different mechanisms. We present results on a realistic rat L2/3 pyramidal neuron model and show their agreement with the NEURON solver.

Purdue University West Lafayette (US)
Openalex Percentile: Top 92%
Neural Networks and Applications
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