Cellular hierarchy for understanding heterogeneity of acute myeloid leukaemia with t(8;21)/RUNX1‐RUNX1T1
Leukaemic differentiation stage independently predicts post-treatment outcomes in t(8;21) AML. Arrest at specific myeloid stages correlates significantly with genetic aberrations, clinical presentation, therapeutic response and survival.
Authors
- He Huang (ORCID: https://orcid.org/0000-0002-1110-2710)
- Shanshan Hu (ORCID: https://orcid.org/0000-0003-1163-8782)
- Lihong Ni
- Weiyan Zheng
- Liang Yue (ORCID: https://orcid.org/0000-0002-0560-6680)
- Jie Sun (ORCID: https://orcid.org/0000-0002-0932-7195)
- Yanmin Zhao (ORCID: https://orcid.org/0000-0003-3857-5574)
- Yibo Wu (ORCID: https://orcid.org/0000-0002-5431-1133)
- Yi Luo (ORCID: https://orcid.org/0000-0001-7051-219X)
- Xiaoyu Lai
- Jian Yu (ORCID: https://orcid.org/0000-0002-7301-1785)
- Yuanyuan Zhu
- Wenjun Wu (ORCID: https://orcid.org/0000-0001-9746-8694)
- Jimin Shi (ORCID: https://orcid.org/0000-0003-0950-0581)
- Xiaolin Yuan
- Zhen Cai (ORCID: https://orcid.org/0009-0001-5822-7502)
- Luxin Yang
- Shanshan Pei
- Lizhen Liu
Institutions
- Chinese Academy of Sciences (CN)
- Wenzhou Medical University (CN)
- Zhejiang Cancer Hospital (CN)
- Cell Technology (China) (HK)
- Jinhua Academy of Agricultural Sciences (CN)
- Hangzhou Cancer Hospital (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Clinical & Translational Immunology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/cti2.70042
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China