Electrosynthesis of Nitrogen-containing Compounds in Nitromethane-Lithium Perchlorate Electrolyte System

Herein, we summarize the electrosynthetic approach toward nitrogen-containing compounds using a nitromethane-lithium perchlorate (MeNO2-LiClO4) electrolyte system. The reactivity of anodically generated cationic intermediates was significantly enhanced in the MeNO2-LiClO4 electrolyte system due to its weak donating nature. This electrolyte promoted various glycosidation and dehydrogenative cross-coupling reactions, yielding N-, C-azanucleosides and (pyrrolo)phenanthridone alkaloids with high regio- and stereoselectivity.