Utilização de remifentanil em antas-brasileiras (<i>Tapirus terrestris</i>) submetidas à anestesia geral

The Brazilian tapir (Tapirus terrestris) is a land mammal that is found in rehabilitation centers throughout Brazil and is frequently subjected to anesthesia to carry out surgical procedures. The present report addresses the use of remifentanil in continuous infusion in two tapirs undergoing general anesthesia for different surgical procedures. Both received detomidine as a sedative, in doses between 20 and 60 mcg/kg, associated with butorphanol or ketamine. Ketamine was the main induction agent, alone or combined with midazolam and propofol. Isoflurane was used to maintain anesthesia, associated with continuous infusions of remifentanil, lidocaine, ketamine and detomidine. Remifentanil (1 and 2 mcg/kg/h) provided an improvement in anesthetic depth, although there was a need for postoperative analgesic rescue. Mild hypotension and bradycardia were observed after the start of the remifentanil infusion, varying more significantly in the second case, possibly influenced by anemia, intraoperative bleeding, and concomitant infusion of alpha-2 agonists. Anesthetic recovery was fast in both cases, without cardiorespiratory compromise. Additional studies are needed to evaluate the analgesic potential and impact of remifentanil in reducing the minimum alveolar concentration (MAC) of isoflurane and its applications in tapirs.

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Publication Details

Journal
PubVet
Published
2025-05-29
DOI
https://doi.org/10.31533/pubvet.v19n05e1779
Primary Topic
Veterinary Pharmacology and Anesthesia
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article
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article

Utilização de remifentanil em antas-brasileiras (Tapirus terrestris) submetidas à anestesia geral

Victória Gabriela Das Neves, Paula Cristina Guimarães, Larissa Carneiro Coutinho Caetano, Michele Andrade de Barros et al.
PubVet
Veterinary Pharmacology and Anesthesia
article

Utilização de remifentanil em antas-brasileiras (Tapirus terrestris) submetidas à anestesia geral

Victória Gabriela Das Neves, Paula Cristina Guimarães, Larissa Carneiro Coutinho Caetano, Michele Andrade de Barros, Yasmin Naiadini Centeno Borges, Camila Alves Sobral, Bruna Maria Sarri, Carolina Akel Ferruccio, João Flávio Panattoni Marins
article en

Abstract

The Brazilian tapir (Tapirus terrestris) is a land mammal that is found in rehabilitation centers throughout Brazil and is frequently subjected to anesthesia to carry out surgical procedures. The present report addresses the use of remifentanil in continuous infusion in two tapirs undergoing general anesthesia for different surgical procedures. Both received detomidine as a sedative, in doses between 20 and 60 mcg/kg, associated with butorphanol or ketamine. Ketamine was the main induction agent, alone or combined with midazolam and propofol. Isoflurane was used to maintain anesthesia, associated with continuous infusions of remifentanil, lidocaine, ketamine and detomidine. Remifentanil (1 and 2 mcg/kg/h) provided an improvement in anesthetic depth, although there was a need for postoperative analgesic rescue. Mild hypotension and bradycardia were observed after the start of the remifentanil infusion, varying more significantly in the second case, possibly influenced by anemia, intraoperative bleeding, and concomitant infusion of alpha-2 agonists. Anesthetic recovery was fast in both cases, without cardiorespiratory compromise. Additional studies are needed to evaluate the analgesic potential and impact of remifentanil in reducing the minimum alveolar concentration (MAC) of isoflurane and its applications in tapirs.

PubVetVol. 19(05)
Pontifícia Universidade Católica de Campinas (BR)
Openalex Percentile: Top 83%
Veterinary Pharmacology and Anesthesia
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Utilização de remifentanil em antas-brasileiras (<i>Tapirus terrestris</i>) submetidas à anestesia geral — Victória Gabriela Das Neves, Paula Cristina Guimarães, et al. · PubVet (2025) | TGRS Research Map | TGRS