Selenium dioxide-mediated oxidative annulation of sulfonyl <i>o</i>-hydroxyacetophenones with acetophenones. One-pot synthesis of aurone analogs

Selenium dioxide-mediated one-pot oxidative annulation of sulfonyl <i>o</i>-hydroxyacetophenones with acetophenones generates good yields of aurone analogs in refluxing dioxane under dry air atmosphere conditions. A plausible mechanism is proposed and discussed here. In the overall reaction process, selenium-containing compounds were generated as byproducts. Various oxidant-promoted conditions were also investigated for one-pot annulation.

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Publication Details

Journal
Organic & Biomolecular Chemistry
Published
2025-01-01
DOI
https://doi.org/10.1039/d5ob00989h
Primary Topic
Synthesis of Organic Compounds
Type
article
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article

Selenium dioxide-mediated oxidative annulation of sulfonyl o-hydroxyacetophenones with acetophenones. One-pot synthesis of aurone analogs

Yuan-Han Liu, Meng‐Yang Chang
Organic & Biomolecular Chemistry
Synthesis of Organic Compounds
article

Selenium dioxide-mediated oxidative annulation of sulfonyl o-hydroxyacetophenones with acetophenones. One-pot synthesis of aurone analogs

Yuan-Han Liu, Meng‐Yang Chang
article en

Abstract

Selenium dioxide-mediated one-pot oxidative annulation of sulfonyl <i>o</i>-hydroxyacetophenones with acetophenones generates good yields of aurone analogs in refluxing dioxane under dry air atmosphere conditions. A plausible mechanism is proposed and discussed here. In the overall reaction process, selenium-containing compounds were generated as byproducts. Various oxidant-promoted conditions were also investigated for one-pot annulation.

Organic & Biomolecular ChemistryVol. 23(29)
Kaohsiung Medical University (TW), National Pingtung University of Science and Technology (TW), Kaohsiung Medical University Chung-Ho Memorial Hospital (TW)
Openalex Percentile: Top 82%
Synthesis of Organic Compounds
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