Analyzing Moringa oleifera Extract’s Antidiabetic Effects with an Osmotic Pump Delivery System

The growing prevalence of diabetes necessitates novel therapeutic approaches that enhance both efficacy and patient adherence. Thisstudy examinesthe antidiabetic efficacy of Moringa oleifera extract delivered via an osmotic pump system in a streptozotocin-induced diabetic rat model, hypothesizing that this advanced delivery mechanism improves bioavailability and extends the duration of pharmacological action. The formulation comprised Moringa oleifera extract, quercetin, and several excipients.Experimental evaluationsmeasured fasting blood glucose levels, bodyweight changes, and biochemical markers of hepatic and renal function, comparing the osmotic pump–based treatment group to standard diabetic controls. Statistical analyses will discern the significance of observed therapeutic benefits, thereby contributing to the evidence base for phytopharmaceuticals in diabetes management and underscoring the potential of osmotic drug delivery systems to enhance clinical outcomes.

Authors

Publication Details

Journal
International Journal of Drug Delivery Technology
Published
2025-01-01
DOI
https://doi.org/10.25258/ijddt.15.2.11
Primary Topic
Moringa oleifera research and applications
Type
article
Field-Weighted Citation Impact
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article

Analyzing Moringa oleifera Extract’s Antidiabetic Effects with an Osmotic Pump Delivery System

Kiran Bhise, Shital Nehere
International Journal of Drug Delivery Technology
Moringa oleifera research and applications
article

Analyzing Moringa oleifera Extract’s Antidiabetic Effects with an Osmotic Pump Delivery System

Kiran Bhise, Shital Nehere
article en

Abstract

The growing prevalence of diabetes necessitates novel therapeutic approaches that enhance both efficacy and patient adherence. Thisstudy examinesthe antidiabetic efficacy of Moringa oleifera extract delivered via an osmotic pump system in a streptozotocin-induced diabetic rat model, hypothesizing that this advanced delivery mechanism improves bioavailability and extends the duration of pharmacological action. The formulation comprised Moringa oleifera extract, quercetin, and several excipients.Experimental evaluationsmeasured fasting blood glucose levels, bodyweight changes, and biochemical markers of hepatic and renal function, comparing the osmotic pump–based treatment group to standard diabetic controls. Statistical analyses will discern the significance of observed therapeutic benefits, thereby contributing to the evidence base for phytopharmaceuticals in diabetes management and underscoring the potential of osmotic drug delivery systems to enhance clinical outcomes.

International Journal of Drug Delivery TechnologyVol. 15(02)
Openalex Percentile: Top 88%
Moringa oleifera research and applications
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