Formulation and Evaluation of Aegle marmelos Infused Anti-ulcerative Toothpaste

Aegle marmelos, commonly referred to as Bael, is renowned for its therapeutic potential, largely attributed to its rich content of bioactive flavonoids such as anthocyanins and betacyanins. These phytoconstituents are associated with notable antioxidant and anti-ulcer effects, primarily due to their capacity to neutralize free radicals. This investigation focuses on formulating a herbal toothpaste incorporating Aegle marmelos fruit extract, with the aim of aiding in the prevention and treatment of oral ulcers. The research encompassed both the development and comprehensive evaluation of the toothpaste formulation. Key quality parameters assessed included physical appearance, pH, consistency, foaming ability, sharpness of abrasive particles, spreadability, moisture level, and volatile matter content; all essential for product performance and consumer acceptability. The antimicrobial efficacy of the herbal toothpaste was examined through zone of inhibition studies against oral pathogens such as Bacillus subtilis and Staphylococcus aureus. Furthermore, the antioxidant activity was assessed through the DPPH free radical scavenging method, a well-established and commonly employed technique. Quantitative analysis of flavonoids was also performed, given their crucial role in therapeutic effectiveness. Overall, the results demonstrated that the toothpaste enriched with Aegle marmelos extract possesses significant antioxidant and antimicrobial activity, supporting its potential use as a natural remedy for managing and preventing mouth ulcers.

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Publication Details

Journal
International Journal of Drug Delivery Technology
Published
2025-01-01
DOI
https://doi.org/10.25258/ijddt.15.2.8
Primary Topic
Diverse Scientific Research Studies
Type
article
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article

Formulation and Evaluation of Aegle marmelos Infused Anti-ulcerative Toothpaste

Dinanath Gaikwad, Firoj Allauddin Tamboli, Dipak Mali, Vijaykumar Tanajirao Pawar et al.
International Journal of Drug Delivery Technology
Diverse Scientific Research Studies
article

Formulation and Evaluation of Aegle marmelos Infused Anti-ulcerative Toothpaste

Dinanath Gaikwad, Firoj Allauddin Tamboli, Dipak Mali, Vijaykumar Tanajirao Pawar, Sanjivani D Mulik, Arya A Musale
article en

Abstract

Aegle marmelos, commonly referred to as Bael, is renowned for its therapeutic potential, largely attributed to its rich content of bioactive flavonoids such as anthocyanins and betacyanins. These phytoconstituents are associated with notable antioxidant and anti-ulcer effects, primarily due to their capacity to neutralize free radicals. This investigation focuses on formulating a herbal toothpaste incorporating Aegle marmelos fruit extract, with the aim of aiding in the prevention and treatment of oral ulcers. The research encompassed both the development and comprehensive evaluation of the toothpaste formulation. Key quality parameters assessed included physical appearance, pH, consistency, foaming ability, sharpness of abrasive particles, spreadability, moisture level, and volatile matter content; all essential for product performance and consumer acceptability. The antimicrobial efficacy of the herbal toothpaste was examined through zone of inhibition studies against oral pathogens such as Bacillus subtilis and Staphylococcus aureus. Furthermore, the antioxidant activity was assessed through the DPPH free radical scavenging method, a well-established and commonly employed technique. Quantitative analysis of flavonoids was also performed, given their crucial role in therapeutic effectiveness. Overall, the results demonstrated that the toothpaste enriched with Aegle marmelos extract possesses significant antioxidant and antimicrobial activity, supporting its potential use as a natural remedy for managing and preventing mouth ulcers.

International Journal of Drug Delivery TechnologyVol. 15(02)
Openalex Percentile: Top 74%
Diverse Scientific Research Studies
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