MINFLUX: μs and nm precision 3D tracking of dynamic lipid mobility on nanoparticles

MINFLUX microscopy opened unique opportunities to investigate complex molecular systems at a single molecule level with μs temporal and nm spatial resolutions in 3D. Here, we demonstrate its use for the characterization of nanomaterials, providing a framework for MINFLUX imaging and data analysis tailored to understanding the complex dynamics of nanosized Silica-Supported Lipid Bilayers (SSLBs).

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Publication Details

Journal
Nanoscale
Published
2025-01-01
DOI
https://doi.org/10.1039/d5nr00948k
Primary Topic
Advanced Fluorescence Microscopy Techniques
Type
article
Field-Weighted Citation Impact
0.00

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article

MINFLUX: μs and nm precision 3D tracking of dynamic lipid mobility on nanoparticles

Ziqiang Huang, Timo Zimmermann, Laura Woythe, Laurence W. Fitzpatrick et al.
4 links
Nanoscale
Advanced Fluorescence Microscopy Techniques
article

MINFLUX: μs and nm precision 3D tracking of dynamic lipid mobility on nanoparticles

Ziqiang Huang, Timo Zimmermann, Laura Woythe, Laurence W. Fitzpatrick, Lorenzo Albertazzi, Sebastian Schnorrenberg
article en

Abstract

MINFLUX microscopy opened unique opportunities to investigate complex molecular systems at a single molecule level with μs temporal and nm spatial resolutions in 3D. Here, we demonstrate its use for the characterization of nanomaterials, providing a framework for MINFLUX imaging and data analysis tailored to understanding the complex dynamics of nanosized Silica-Supported Lipid Bilayers (SSLBs).

NanoscaleVol. 17(28)
Eindhoven University of Technology (NL)
Boehringer Ingelheim, European Molecular Biology Laboratory, Boehringer Ingelheim Stiftung, European Research Council
Openalex Percentile: Top 89%
Advanced Fluorescence Microscopy Techniques
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