HIV‐1 testing in the context of expanding PrEP modalities
Optimal strategies to detect HIV-1 acquisition among users of different PrEP modalities are evolving. While new guidance from the WHO recommends HIV-1 testing by serological assays or self-testing with PrEP use, feasible plans for clinical management of rare cases of breakthrough on PrEP and ambiguous diagnoses are still needed. The data from PrEP studies and scale-up will help us assess the value of different tests and testing approaches for their inclusion in HIV detection algorithms across PrEP modalities.
Authors
- Jana L. Jacobs (ORCID: https://orcid.org/0000-0002-0322-585X)
- John W. Mellors (ORCID: https://orcid.org/0000-0002-3737-9742)
- Njambi Njuguna (ORCID: https://orcid.org/0000-0002-0969-3849)
- Kristine Torjesen (ORCID: https://orcid.org/0000-0002-3439-1199)
- Urvi M. Parikh (ORCID: https://orcid.org/0000-0002-4016-0629)
Institutions
- Family Health International 360 (US)
- University of Pittsburgh (US)
Publication Details
- Journal
- Journal of the International AIDS Society
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1002/jia2.26491
- Citations
- 3
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 4.19
Funders
- United States Agency for International Development
- U.S. President’s Emergency Plan for AIDS Relief
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases