A non-invasive, reference region-based method for quantification of cerebral blood flow and oxygen metabolism using oxygen-15 labeled gases and positron emission tomography.
A simple method for noninvasive quantification of CBF, CBV, OEF, and CMRO<sub>2</sub> using PET and oxygen-15 labeled gases could be developed based on the steady-state method. This method can be used to investigate the pathophysiology of occlusive cerebrovascular disease.
Authors
- Shiro Ishii (ORCID: https://orcid.org/0000-0002-5274-877X)
- Masanobu Ibaraki (ORCID: https://orcid.org/0000-0002-4280-6470)
- Hiroshi Ito (ORCID: https://orcid.org/0000-0002-3581-4798)
- Hitoshi Kubo (ORCID: https://orcid.org/0000-0001-7269-7036)
- Ryo Yamakuni (ORCID: https://orcid.org/0000-0003-0265-5636)
- Naoyuki Ukon (ORCID: https://orcid.org/0000-0002-6715-582X)
- Kazuhiro Takahashi (ORCID: https://orcid.org/0000-0001-7855-575X)
- Kenji Fukushima (ORCID: https://orcid.org/0000-0003-2844-2284)
Institutions
- Fukushima Medical University (JP)
- Institute of Brain and Blood Vessels (JP)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22038/aojnmb.2025.81433.1578
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science