Microbial Challenge of Stable Compounded Clozapine Suspensions in Plastic Bottles.

The 25-mg/mL and 50-mg/mL clozapine suspensions have been demonstrated to effectively control bacterial and fungal contamination, as judged by the USP Chapter <51> Antimicrobial Effectiveness Test. This bracketed formulation has been previously demonstrated to retain more than 95% of its initial active concentration when stored at 4oC or 25oC for 120-days.

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PubMed
Published
2025-06-29
Primary Topic
Antifungal resistance and susceptibility
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article
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article

Microbial Challenge of Stable Compounded Clozapine Suspensions in Plastic Bottles.

Jason A. Gross, Scott E. Walker, Hanif Sachedina, Jessica Berzy et al.
PubMed
Antifungal resistance and susceptibility
article

Microbial Challenge of Stable Compounded Clozapine Suspensions in Plastic Bottles.

Jason A. Gross, Scott E. Walker, Hanif Sachedina, Jessica Berzy, Arif Virji, Erica Cull
article en

Abstract

The 25-mg/mL and 50-mg/mL clozapine suspensions have been demonstrated to effectively control bacterial and fungal contamination, as judged by the USP Chapter <51> Antimicrobial Effectiveness Test. This bracketed formulation has been previously demonstrated to retain more than 95% of its initial active concentration when stored at 4oC or 25oC for 120-days.

PubMedVol. 29(3)
University of Toronto (CA), Cégep de Saint-Laurent (CA), Workers Compensation Board of Alberta (CA), Imperial College of Toronto (CA)
Openalex Percentile: Top 80%
Antifungal resistance and susceptibility
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