Down-regulation of neuregulin2 (NRG2) following spinal cord injury in C57BL/6 mice: Its implications in therapeutic potential.
The NRG2-ErbB4 signaling pathway was inhibited after SCI in mice. NRG2 promotes the healing of HT22 cells after scratch injury, and the mechanism of NRG2 in the treatment of SCI may be ascribed to the activation of PI3K-Akt signaling pathways downstream to NRG2.
Authors
- Kai-Ye Hua
- Song Quan (ORCID: https://orcid.org/0000-0002-5190-4179)
- Weijiang Zhao (ORCID: https://orcid.org/0000-0002-6556-2827)
- Shuai Zhang (ORCID: https://orcid.org/0000-0002-7876-5578)
- Yanjun Liu (ORCID: https://orcid.org/0000-0002-0206-7685)
- Ke Qi (ORCID: https://orcid.org/0000-0002-3089-2041)
Institutions
- Jiangnan University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22038/ijbms.2025.83787.18131
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Government of Jiangsu Province